Exercise training increases basal tone in arterioles distal to chronic coronary occlusion
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چکیده
منابع مشابه
Exercise training increases basal tone in arterioles distal to chronic coronary occlusion.
Endurance exercise training increases basal active tone in coronary arteries and enhances myogenic tone in coronary arterioles of control animals. Paradoxically, exercise training has also been shown to augment nitric oxide production and nitric oxide-mediated relaxation in coronary arterioles. The purpose of the present study was to examine the effect of exercise training on basal active tone ...
متن کاملExercise training enhances vasodilation responses to vascular endothelial growth factor in porcine coronary arterioles exposed to chronic coronary occlusion.
BACKGROUND Chronic coronary occlusion (CCO) impairs endothelial function of distal collateral-dependent microvasculature; however, long-term exercise training (EX) seems to improve endothelial dysfunction. We hypothesized that EX enhances vasodilation responses to vascular endothelial growth factor (VEGF165), mediated via nitric oxide (NO), in arterioles exposed to CCO. METHODS AND RESULTS Th...
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We previously reported that canine collateral-dependent coronary arteries exhibit impaired relaxation to adenosine but not sodium nitroprusside. In contrast, exercise training enhances adenosine sensitivity of normal porcine coronary arteries. These results stimulated the hypothesis that chronic coronary occlusion and exercise training produce differential effects on cAMP- versus cGMP-mediated ...
متن کاملExercise training improves endothelium-mediated vasorelaxation after chronic coronary occlusion.
The present study evaluated combined effects of chronic coronary occlusion and exercise training on endothelial function. Gradual occlusion was produced by placement of an ameroid constrictor around the proximal left circumflex (LCX) coronary artery of female swine. Two months after placement of the ameroid, animals were restricted to their pens or exercise trained for 16 wk. Epicardial arterie...
متن کاملExercise training increases K1-channel contribution to regulation of coronary arterial tone
Bowles, D. K., M. H. Laughlin, and M. Sturek. Exercise training increases K1-channel contribution to regulation of coronary arterial tone. J. Appl. Physiol. 84(4): 1225–1233, 1998.—The present study examined whether regulation of coronary tone in conduit arteries (.1.0 mm ID) is altered by exercise training. Yucatan miniature swine were treadmill trained for 16–20 wk (Ex) and compared with sede...
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ژورنال
عنوان ژورنال: American Journal of Physiology-Heart and Circulatory Physiology
سال: 2006
ISSN: 0363-6135,1522-1539
DOI: 10.1152/ajpheart.00973.2005